1H-苯并三唑-1-基氧代三(二甲氨基)磷鎓 六氟磷酸盐

1H-Benzotriazol-1-yloxytris(dimethylamino)phosphonium hexafluorophosphate is used as a reagent for peptide coupling, lactonization, selective esterification, amidation of alfa amino acids without racemization and synthesis of magnolamide for antioxidative activity and catalyst for 9-acridinecaroboxamide derivative. It is also used as a precursor for the synthesis of phenyl esters of amino acids. It acts as a substitute for (Benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate (BOP) reagent.

Moisture and light sensitive. Incompatible with strong oxidizing agents. Store in a cool place. Keep the container tightly closed.

MFCD00011948

260-279-1

C₁₂H₂₂F₆N₆OP₂

442.29

ca 138° dec.

Keep Cold. Moisture Sensitive. Light Sensitive. Store under Nitrogen.

Crystalline powder

Soluble in methanol, acetone and dichloromethane. Insoluble in water.

4287025

II

11-36/37/38-44
Highly flammable.Irritating to eyes, respiratory system and skin.Risk of explosion if heated under confinement.

4.1

26-37-60
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.This material and its container must be disposed of as hazardous waste

  

否

  

H228-H315-H319-H335
Flammable solid.Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

P210-P261-P280-P305+P351+P338-P405-P501a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking.Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves/protective clothing/eye protection/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.