2-(2-溴乙基)-1,3-二氧杂环乙烷

2-(2-Bromoethyl)-1,3-dioxane, Provides a useful means of introducing a masked ??-formylethyl group. In comparison with the corresponding dioxolane (following entry), the dioxane is more stable to acid, and the Grignard is thermally stable. Reaction of the Grignard with an acid chloride gives the ketone in high yield without further reaction to the tertiary alcohol. Subsequent hydrolysis of the 1,3-dioxane gives the -ketoaldehyde. It is also used as a pharmaceutical intermediate.

Air, Heat sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Keep away from oxidizing agents. Stable under recommended storage conditions.

MFCD00006567

251-716-7

C₆H₁₁BrO₂

195.06

67-70°/3mm

96°(204°F)

1.434

1.4820

Keep Cold. Store under Nitrogen.

Liquid

It is not soluble in water but soluble in organic solvent such as ethanol.

1421628

36/37/38
Irritating to eyes, respiratory system and skin.

23-26-37-60
Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer).In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.This material and its container must be disposed of as hazardous waste

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H315-H319-H335
Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.