3-溴-5-碘苯甲酸

3-Bromo-5-iodobenzoic acid may be used in the preparation of the following: • Phenyl(3-bromo-5-iodo)benzoate. • As starting reagent for the large-scale synthesis of the thromboxane receptor antagonist 3-{3-[2-(4-chlorobenzenesulfonamido)ethyl]-5-(4-fluorobenzyl)phenyl}propionic acid, via regioselective Heck cross-coupling reaction. • Methyl 3-bromo-5-iodobenzoate. • 3-Bromo-5-(triisopropylsilylethynyl)benzoic acid, via Sonogashira coupling reaction. • Trifluoroacetophenone.

Light Sensitive. Protect from light. Store away from oxidizing agents.

MFCD00191851

C₇H₄BrIO₂

326.92

218-221°

Light Sensitive. Ambient temperatures.

Powder

Soluble in methanol. Sparingly Soluble (0.20 g/L) (25°C), Calc.

3240837

36/37/38
Irritating to eyes, respiratory system and skin.

26-37
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

否

 

H315-H319-H335
Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.