18-冠-6醚

18-Crown-6 is used as an efficient phase transfer catalyst and as a complexing agent with a variety of small cation. It is involved in the synthesis of diaryl ethers, diaryl thioethers, and diarylamines mediated by potassium fluoride-alumina and 18-crown-6. It facilitates the solubility of potassium permanganate in benzene, which is used for oxidizing the organic compounds. It is used to accelerate various substitution reactions as well as enhances the power of nucleophiles such as potassium acetate. It is utilized in the alkylation reactions in the presence of potassium carbonate, N-alkylation of glutarimide and succinimide with dimethylcarbonate. The complex formed by its reaction with potassium cyanide acts as a catalyst in the cyanosilylation of aldehydes, ketones and quinines with trimethylsilyl cyanide (TMSCN).

Hygroscopic. Incompatible with strong oxidizing agents and strong acids.

MFCD00005113

241-473-5

C₁₂H₂₄O₆

264.32

37-41°

116°/0.2mm

109°(228°F)

1.175

Hygroscopic. Ambient temperatures.

Crystalline lumps

Soluble in water.

1619616

14,2602

22-36
Harmful if swallowed.Irritating to eyes.

26-36
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing.

MP4500000

 

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H302-H313-H319
Harmful if swallowed.May be harmful in contact with skin.Causes serious eye irritation.

P280i-P264-P305+P351+P338-P301+P312a-P337+P313-P501a
Wear eye/face protection.Wash thoroughly after handling.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.If eye irritation persists: Get medical advice/attention.Dispose of contents/container in accordance with local/regional/national/international regulations.