2,4-二溴噻唑

2,4-Dibromothiazole is applied as a building block in a synthesis of Melithiazole C employing a highly (E)-selective cross-metathesis between the derived 4-vinylthiazole and a dienote side-chain. It is also used as an intermediate in the preparation of various 2,4-disubstituted thiazole derivatives with biologically active properties such as survival motor neuron (SMN) protein modulators.

Air sensitive. Incompatible with oxidizing agents.

MFCD01318994

C₃HBr₂NS

242.92

80-84°

Store under Nitrogen. Ambient temperatures.

Solid

22-37/38-41
Harmful if swallowed.Irritating to respiratory system and skin.Risk of serious damage to eyes.

26-36/37/39-60
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing, gloves and eye/face protection.This material and its container must be disposed of as hazardous waste

 

否

  

H302-H315-H318-H335
Harmful if swallowed.Causes skin irritation.Causes serious eye damage.May cause respiratory irritation.

P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.