N,N'-二环己基碳二亚胺

N,N'-Dicyclohexylcarbodiimide is a carboxyl activating reagent used in peptide synthesis. It acts as a dehydrating agent for the preparation of amides, ketones and nitriles. It is involved in the preparation of esters by reacting tertiary alcohols with carboxylic acid. It is utilized for the stereo chemical inversion of secondary alcohols by forming formyl ester followed by saponification. It is associated with dimethyl sulfoxide and used in Pfitzner-Moffatt oxidation to convert alcohols into aldehydes and ketones.

Incompatible with strong oxidizing agents.

MFCD00011659

208-704-1

C₁₃H₂₂N₂

206.33

33-36°

154-156°/11mm

138°(280°F)

Moisture Sensitive. Store under Nitrogen. Ambient temperatures.

Solid

Soluble in methanol, chloroform, dichloromethane, acetonitrile, tetrahydrofuran and dimethylformamide. Insoluble in water.

610662

14,3096

III

22-24-41-43
Harmful if swallowed.Toxic in contact with skin.Risk of serious damage to eyes.May cause sensitization by skin contact.

6.1

24-26-37/39-45
Avoid contact with skin.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable gloves and eye/face protection.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).

FF2160000

是

  

H302-H311-H318-H317
Harmful if swallowed.Toxic in contact with skin.Causes serious eye damage.May cause an allergic skin reaction.

P261-P280-P305+P351+P338-P310a-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves/protective clothing/eye protection/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.