哌啶-4-羧酸乙酯

It is used as a reactant for synthesis of SMN protein modulators, β-aryl and β-amino-substituted aliphatic esters by rhodium catalyzed tandem double bond migration/conjugate addition, nitroethylenediamines by nucleophilic ring opening of nitroimidazolidinone. It is also involved in the reactions of RhoA inhibitors for cardiovascular disease therapy and saccharin derived Mannich bases as antimicrobials and antioxidants. It is employed as a reactant for one-pot reductive amination and Suzuki-Miyaura cross coupling of formyl aryl and heteroaryl MIDA boronates.

Store at room temperature. Incompatible with strong oxidizing agents.

MFCD00006003

214-416-7

C₈H₁₅NO₂

157.21

203-205°

80°(176°F)

1.021

1.4600

Ambient temperatures.

Liquid

Fully miscible with water.

118419

36/37/38
Irritating to eyes, respiratory system and skin.

26-37
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

否

 

H227-H315-H319-H335
Combustible liquid.Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

P210e-P261-P280a-P305+P351+P338-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.