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3-(4-氟苯甲酰)丙酸
3-(4-Fluorobenzoyl)propionic Acid
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产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
3046866 | 5g | 562 | |||
3046866 | 25g | 2220 |
产品别名
366-77-8
3-(4-氟苯甲酰)丙酸
3-(4-Fluorobenzoyl)propionic Acid
基本信息
应用 | 7-Fluoro-1-tetralone was prepared from 3-(4-fluorobenzoyl)-propionic acid by Wolff-Kishner reduction followed by ring closure with polyphosphoric acid and other substituted 1-tetralones where commercially available. Reduction of 3-(4-fluorobenzoyl)propionic acid with an excess of tert-butylamine borane (TBAB) in the presence of AlCl3 provided 4-(4-fluorophenyl)-1-butanol (87) in 63% yield for the synthesis of LM-1507 sodium salt. Penfluridol 1-[4,4-bis(4-fluorophenyl)butyl]-4-(4-chloro-3-trifluoromethylphenyl)- 4-hydroxypiperidine, C 28 H 27 ClF 5 NO, M r 523.99, mp 105 - 107?°C, is obtained by reducing the ketone of 3-(4-fluorobenzoyl)propionic acid into a lactone. |
备注 | Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents. |
MDL | MFCD00002793 |
EINECS | 206-679-1 |
分子式 | C10H9FO3 |
分子量 | 196.18 |
熔点 | 99-103° |
灵敏度 | Ambient temperatures. |
形态 | Crystalline powder |
溶解性 | Insoluble in water. |
Beilstein | 958145 |
危险类别 | 36/37/38 Irritating to eyes, respiratory system and skin. |
安全信息
安全等级 | 26-37-60 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.This material and its container must be disposed of as hazardous waste |
TSCA | 否 |
GHS危害和防范说明
GHS符号 | ![]() |
Hazard Statements | H315-H319-H335 Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation. |
Precautionary Statements | P280g-P305+P351+P338 Wear protective gloves.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. |