高哌嗪

Homopiperazine is used to prepare 1,4-bis-(2-thiazolyl)-1,4-diazacycloheptane by reacting with 2-bromo-thiazole. It acts as an intermediate for repaglinide and fasudil hydrochloride. It is also used in the preparation of potent H3 receptor antagonists, which is used for the treatment of neurodegenerative conditions. Further, it is used in vesicant, cosmetic, emulsifier and energetic material. It acts as a corrosion inhibitor for iron. In pharmaceuticals, it is employed as antipyretic and reducing blood sugar, adiposity, calm, antipsychotic and anti-nervous.

Hygroscopic. Air sensitive. Incompatible with strong oxidizing agents and strong acids.

MFCD00006933

208-016-1

C₅H₁₂N₂

100.17

38-44°

168-170°

64°(147°F)

0.95

Hygroscopic. Air Sensitive. Ambient temperatures.

Solid

Soluble in water.

102711

II

21-34
Harmful in contact with skin.Causes burns.

8

26-36/37/39-45
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing, gloves and eye/face protection.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).

HM3850000

  

是

  

H303-H312-H314-H318
May be harmful if swallowed.Harmful in contact with skin.Causes severe skin burns and eye damage.Causes serious eye damage.

P280-P305+P351+P338-P309-P310
Wear protective gloves/protective clothing/eye protection/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF exposed or if you feel unwell:Immediately call a POISON CENTER or doctor/physician.