丙二酸亚异丙酯

Isopropylidene malonate is an important reagent in synthetic chemistry and involved in the formation of new C-C bonds, rings, amides, esters, and acids. The presence of carbonyl groups at C-4 and C-6 positions favors the alkylation and acylation reactions due to its acidic nature. It is also employed as an antimicrobial agent. It is used in the preparation of 4-pyridyl-substituted heterocycles, 2-substituted indoles, isofraxidin and macrocyclic beta-keto lactones. Further, it is involved in the Knoevenagel condensation reaction with aldehydes.

Store in a cool place. Incompatible with strong oxidizing agents.

MFCD00006638

217-992-8

C₆H₈O₄

144.13

92-96°

Moisture Sensitive. Ambient temperatures.

Crystalline powder

Soluble in water. Slightly soluble in ethanol and chloroform.

117310

14,5817

III

36/37/38
Irritating to eyes, respiratory system and skin.

9

26-37
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

JH0800000

是

 

H315-H319-H335
Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.