香豆灵酸甲酯

Methyl coumalate is a 2-pyrone and acts as dienophile in Diels-Alder reaction. It reacts with 1,3-butadienes at 100?°C to yield tetrahydrocoumarins and 4-methoxycarbonyltricyclo[3.2.1.02,7]octenes. It also reacts with cyclohexadiene to afford tetrahydronaphthalene-2-carboxylate. It undergoes Diels-Alder reaction with unactivated alkenes to afford para-substituted adducts. It has been used as reagent in phosphine-catalyzed [4+3] annulation of modified allylic carbonates. It was also used in the preparation of 7-carboxyquinolizinium derivatives.

Stable under recommended storage conditions. Incompatible with oxidizing agents.

MFCD00010120

227-871-1

C₇H₆O₄

154.12

68-72°

178-180°/60mm

Ambient temperatures.

Powder

Freely soluble in dichloromethane.

14,2557

否