2-甲基环戊烷-1,3-二酮

2-Methylcyclopentane-1,3-dione is an efficient synthon for the synthesis of (?±)-α-cuparenone. The alkylation of 2-methylcyclopentane-1,3-dione (A) with 2-(1-naphthyl)ethyl bromide gives only the O-alkylation product. Mixtures of C- and O-alkyl derivatives are obtained. Michael addition of 2-methylcyclopentane-1,3-dione to methyl vinyl ketone in water gives 2-methyl-2-(3-oxo- butyl)-1,3-cyclopentanedione (3), an important intermediate of natural product chemistry. 2-Methylcyclopentane-1, 3-dione is an efficient synthon for the synthesis of (?±)-α-cuparenone.

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.

MFCD00001406

212-153-2

C₆H₈O₂

112.13

212-216°

Ambient temperatures.

Powder/crystals

Solubility in hot Methanol (almost transparency).

1237255

否