2-琥珀酰亚胺基-1,1,3,3-四甲基脲鎓四氟硼酸酯

2-Succinimido-1,1,3,3-tetramethyluronium tetrafluoroborate (TSTU) acts as an efficient coupling agent through rapid activation of carboxylic acids to form N-succinimidyl active esters, which react with primary amines to form carboxamides. It is effective even in the presence of water. TSTU is selective towards amines in the presence of alcoholic group. It is employed as a coupling regent in the synthesis of peptides. With amine-protected alpha-amino acids, it brings about coupling without significant epimerization. It is useful for linking of sensor molecules with amino groups to amino-functionalized AFM (atomic force microscope) tips.

Moisture sensitive, Incompatible with strong oxidizing agents.

MFCD00077875

000-000-0

C₉H₁₆BF₄N₃O₃

301.05

195-200°

Moisture Sensitive. Ambient temperatures.

Soluble in acetonitrile, DMF, chloroform, dichlorormethane and acetonitrile.

22-36/37/38
Harmful if swallowed.Irritating to eyes, respiratory system and skin.

26-36/37
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing and gloves.

 

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H301-H315-H319-H335
Toxic if swallowed.Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

P261-P280a-P301+P310a-P305+P351+P338-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.