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产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3073706 | 10 MG | 1370 | |||
| 3073706 | 25 MG | 3540 |
产品别名
2259-96-3
Cyclothiazide
6-Chloro-3,4-dihydro-3-(2-norbornen-5-yl)-2H-1,2-4-benzothiadiazine-7-sulfonamide 1,1-dioxide
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C14H16ClN3O4S2 |
| Molecular weight | 389.88 |
| EC number【EC 号】 | 218-859-7 |
| MDL number | MFCD00210192 |
| PubChem Substance ID【PubChem化学物质编号】 | 24278350 |
| NACRES | NA.77 |
| General description【一般描述】 | Cyclothiazide is a benzothiadiazine, which has a similar structure to diazoxide. |
| Application【应用】 | Cyclothiazide has been used as a α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR) desensitization blocker to study the effects of γ2 on receptor desensitization. |
| Biochem/physiol Actions【生化/生理作用】 | Blocks the rapid desensitization of the AMPA glutamate receptors and markedly prolongs the decay time of the evoked excitatory post-synaptic current. |
| Features and Benefits【特点和优势】 | This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm. This compound is featured on the Glutamate Receptors (Ion Channel Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here. This compound was developed by Eli Lilly. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here. |
产品性质
| Quality Level【质量水平】 | 200 |
| originator【创始人】 | Eli Lilly |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | [H][C@@]12CC(C3Nc4cc(Cl)c(cc4S(=O)(=O)N3)S(N)(=O)=O)[C@@]([H])(C1)C=C2 |
| InChI | 1S/C14H16ClN3O4S2/c15-10-5-11-13(6-12(10)23(16,19)20)24(21,22)18-14(17-11)9-4-7-1-2-8(9)3-7/h1-2,5-9,14,17-18H,3-4H2,(H2,16,19,20)/t7-,8+,9?,14?/m0/s1 |
| InChI key | BOCUKUHCLICSIY-QJWLJZLASA-N |
| Gene Information | human ... CA1(759), CA4(762), GRIA1(2890), GRIA2(2891), GRIA3(2892), GRIA4(2893) rat ... Gria1(50592) |
| packaging【包装】 | 10 mg in poly bottle 25 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 2 |
| Personal Protective Equipment【个人防护装备】 | dust mask type N95 (US), Eyeshields, Gloves |
