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D4476
| 产品编号： | 3074397 |
| 规格： | ≥98% (HPLC), solid |
| CAS NO： | 301836-43-1 |
| 包装规格： | 1 MG，5 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3074397 | 1 MG | 2300 | |||
| 3074397 | 5 MG | 8300 |
产品别名
301836-43-1
D4476
4-(4-(2,3-Dihydrobenzo[1,4]dioxin-6-yl)-5-pyridin-2-yl-1H-imidazol-2-yl)benzamide
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C23H18N4O3 |
| Molecular weight | 398.41 |
| PubChem Substance ID【PubChem化学物质编号】 | 329798715 |
| NACRES | NA.77 |
| Application【应用】 | D4476 has been used as a casein kinase I inhibitor (CKI) in various experiments. |
| Biochem/physiol Actions【生化/生理作用】 | D4476 may prevent or enhance apoptosis. It triggers tumor suppressor p53 and impairs transcription factor E2F-1. D4476 is a potent, selective ATP-competitive inhibitor of CK1 (casein kinase 1). |
| Features and Benefits【特点和优势】 | This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | solid |
| color【颜色】 | light yellow |
| solubility【溶解性】 | DMSO: ~20 mg/mL H2O: insoluble |
| originator【创始人】 | GlaxoSmithKline |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | NC(=O)c1ccc(cc1)-c2nc(-c3ccccn3)c([nH]2)-c4ccc5OCCOc5c4 |
| InChI | 1S/C23H18N4O3/c24-22(28)14-4-6-15(7-5-14)23-26-20(21(27-23)17-3-1-2-10-25-17)16-8-9-18-19(13-16)30-12-11-29-18/h1-10,13H,11-12H2,(H2,24,28)(H,26,27) |
| InChI key | DPDZHVCKYBCJHW-UHFFFAOYSA-N |
| packaging【包装】 | 1, 5 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |
