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地氯雷他定
Desloratadine
| 产品编号： | 3075087 |
| 规格： | powder, ≥98% (HPLC) |
| CAS NO： | 100643-71-8 |
| 包装规格： | 10 MG，50 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3075087 | 10 MG | 2710 | |||
| 3075087 | 50 MG | 9290 |
产品别名
100643-71-8
地氯雷他定
Desloratadine
8-Chloro-6,11-dihydro-11-(4-piperidinylidene)-5H- benzo[5,6]cyclohepta[1,2,b]pyridine
Clarinex
NSC 675447
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C19H19ClN2 |
| Molecular weight | 310.82 |
| MDL number | MFCD00871949 |
| PubChem Substance ID【PubChem化学物质编号】 | 329798668 |
| NACRES | NA.32 |
| Application【应用】 | Desloratadine has been used to test its effect on embryoid body development in in vitro gastrulation model of P19C5 stem cells. It has also been used as an antihistamine mimic in rats and to treat lung cancer (A549) and glioblastoma (U87) cells in various cellular studies. |
| Biochem/physiol Actions【生化/生理作用】 | Desloratadine is a selective and nonsedating histamine H1 receptor antagonist, an active metabolite of loratadine (Claritin), used to relieve hay fever and allergy symptoms with less drowsiness than other antihistamines; does not significantly inhibits cardiac K+ channels at clinically achievable blood levels. Free from antimuscarinic/anticholinergic effects. |
| Other Notes【其他说明】 | Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. D1069.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin. |
| Legal Information【法律信息】 | Clarinex is a registered trademark of Schering Corp. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| solubility【溶解性】 | DMSO: >10 mg/mL |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | Clc1ccc2c(CCc3cccnc3\C2=C4\CCNCC4)c1 |
| InChI | 1S/C19H19ClN2/c20-16-5-6-17-15(12-16)4-3-14-2-1-9-22-19(14)18(17)13-7-10-21-11-8-13/h1-2,5-6,9,12,21H,3-4,7-8,10-11H2 |
| InChI key | JAUOIFJMECXRGI-UHFFFAOYSA-N |
| Gene Information | human ... HRH1(3269) |
| packaging【包装】 | 10, 50 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
