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Dihydroeponemycin
产品别名
126463-64-7
Dihydroeponemycin
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C20H36N2O6 |
| Molecular weight | 400.51 |
| MDL number | MFCD17215971 |
| PubChem Substance ID【PubChem化学物质编号】 | 329798798 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | Dihydroeponemycin is an active derivative of eponemycin an antitumor antibiotic isolated from Streptomyces hygroscopicus. Dihydroeponemycin labels the catalytic threonine residues of the immunoproteasome subunits LMP2 and LMP7 and the constitutive proteasome subunit X, while epoxomicin covalently modifies the N-terminal catalytic threonine residues of the constitutive proteasome (X and Z) and immunoproteasome (LMP7 and MECL1) subunits. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| optical activity【旋光性】 | [α]/D ±35.7° |
| color【颜色】 | off-white to light tan |
| solubility【溶解性】 | DMSO: ≥1 mg/mL |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | CC(C)CCCCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]1(CO)CO1 |
| InChI | 1S/C20H36N2O6/c1-13(2)7-5-6-8-17(25)21-16(10-23)19(27)22-15(9-14(3)4)18(26)20(11-24)12-28-20/h13-16,23-24H,5-12H2,1-4H3,(H,21,25)(H,22,27)/t15-,16-,20+/m0/s1 |
| InChI key | IUDBVFIQSSOIDB-TWOQFEAHSA-N |
| packaging【包装】 | 1, 5 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H302 |
| Hazard Classifications【危险分类】 | Acute Tox. 4 Oral |
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
