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DIM-C-pPhtBu
产品别名
94944-80-6
DIM-C-pPhtBu
3,3′-[[4-(1,1-Dimethylethyl)phenyl]methylene]bis-1H-indole
1,1-Bis(3-indolyl)-1-(p-t-butylphenyl)methane
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C27H26N2 |
| Molecular weight | 378.51 |
| EC number【EC 号】 | 305-658-5 |
| MDL number | MFCD18082348 |
| PubChem Substance ID【PubChem化学物质编号】 | 329825365 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | DIM-C-pPhtBu, similar to other C-DIMs, exhibits a broad range of anticancer and antitumorigenic activities against multiple tumor types. DIM-C-pPhtBu causes apoptotic cell death of KB cells by activation of endoplasmic reticulum stress through induction of CHOP protein that is associated with the apoptosis in human oral cancer cells. Also it appears to induce an autophagic cell death in drug-resistant ER-negative breast tumors. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥96% (HPLC) |
| form【形式】 | powder |
| storage condition【储存条件】 | desiccated |
| color【颜色】 | light orange to dark orange |
| solubility【溶解性】 | DMSO: >15 mg/mL |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | CC(C)(C)c1ccc(cc1)C(c2c[nH]c3ccccc23)c4c[nH]c5ccccc45 |
| InChI | 1S/C27H26N2/c1-27(2,3)19-14-12-18(13-15-19)26(22-16-28-24-10-6-4-8-20(22)24)23-17-29-25-11-7-5-9-21(23)25/h4-17,26,28-29H,1-3H3 |
| InChI key | NCPVEZRBHNDCIV-UHFFFAOYSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
