您的位置：首页 > 产品中心 > 120279-96-1， 多佐胺
多佐胺
Dorzolamide
产品别名
120279-96-1
多佐胺
Dorzolamide
(4S,6S)-4H-Thieno[2,3-b]thiopyran-2-sulfonamide, 4-(ethylamino)-5,6-dihydro-6-methyl-, 7,7-dioxide
L-671,152
MK-507
4S,6S-Dorzolamide
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C10H16N2O4S3 |
| Molecular weight | 324.44 |
| MDL number | MFCD00865636 |
| PubChem Substance ID【PubChem化学物质编号】 | 329824746 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | Dorzolamide is a potent carbonic anhydrase II inhibitor with an IC50 value of 0.16 nM on human erythrocyte carbonic anhydrase II in vitro. It has been found to lower increased intraocular pressure in open-angle glaucoma and ocular hypertension. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| optical activity【旋光性】 | [α]/D -25 to -35°, c = 1 in methanol |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 5 mg/mL (clear solution, warmed) |
| storage temp.【储存温度】 | room temp |
| SMILES string | CCN[C@H]1C[C@H](C)S(=O)(=O)c2sc(cc12)S(N)(=O)=O |
| InChI | 1S/C10H16N2O4S3/c1-3-12-8-4-6(2)18(13,14)10-7(8)5-9(17-10)19(11,15)16/h5-6,8,12H,3-4H2,1-2H3,(H2,11,15,16)/t6-,8-/m0/s1 |
| InChI key | IAVUPMFITXYVAF-XPUUQOCRSA-N |
| Gene Information | human ... CA2(760) |
| packaging【包装】 | 10, 50 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H302 |
| Precautionary Statements | P264 - P270 - P301 + P312 - P501 |
| Hazard Classifications【危险分类】 | Acute Tox. 4 Oral |
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
