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DPC
产品别名
1382469-39-7
DPC
Di-2-pyridylketone-4-cyclohexyl-4-methyl-3-thiosemicarbazone
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C19H23N5S |
| Molecular weight | 353.48 |
| MDL number | MFCD22666593 |
| PubChem Substance ID【PubChem化学物质编号】 | 329825434 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | DpC is an iron-chelating agent. DpC is an iron-chelating agent. In four separate human pancreatic tumor cell lines, DpC significantly increased the expression and phosphorylation of the growth and metastasis suppressor, N-myc down-stream regulated gene 1 (NDRG1) and the cdk inhibitpr p21CIP1/WAF. DpC completely blocked PANC-1 tumor growth in mouse xenografts. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| storage condition【储存条件】 | protect from light |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 5 mg/mL (clear solution) |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | CN(C1CCCCC1)C(=S)N\N=C(\c2ccccn2)c3ccccn3 |
| InChI | 1S/C19H23N5S/c1-24(15-9-3-2-4-10-15)19(25)23-22-18(16-11-5-7-13-20-16)17-12-6-8-14-21-17/h5-8,11-15H,2-4,9-10H2,1H3,(H,23,25) |
| InChI key | GNLZNQJBZNOUBM-UHFFFAOYSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS06 |
| Signal word【警示用语：】 | Danger |
| Hazard Statements | H301 |
| Precautionary Statements | P301 + P310 |
| Hazard Classifications【危险分类】 | Acute Tox. 3 Oral |
| Storage Class Code【储存分类代码】 | 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects |
| WGK | WGK 3 |
