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益康唑 硝酸盐
Econazole nitrate salt
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3080700 | 5 G | 711 | |||
| 3080700 | 25 G | 3140 | |||
| 3080700 | 100 G | 7190 |
产品别名
24169-02-6
益康唑 硝酸盐
Econazole nitrate salt
1-(2-[(4-Chlorophenyl)methoxy]-2-[2,4-dichlorophenyl]ethyl)-1H-imidazole
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C18H15Cl3N2O · HNO3 |
| Molecular weight | 444.70 |
| EC number【EC 号】 | 246-053-5 |
| MDL number | MFCD00058160 |
| PubChem Substance ID【PubChem化学物质编号】 | 24894567 |
| NACRES | NA.85 |
| General description【一般描述】 | Chemical structure: imidazole |
| Application【应用】 | Econazole is a broad spectrum antimycotic similar to ketoconazole. It has some action against Gram positive bacteria. It is used topically in dermatomycoses as well as orally and parenterally. It is used for studies on processes such as platelet serotonin uptake, prostanoid biosynthesis, EDHF-mediated relaxation, and Ca2+ transport pathways in thymic lymphocytes. |
| Biochem/physiol Actions【生化/生理作用】 | Econazole interacts with 14-α demethylase, a cytochrome P-450 enzyme necessary to convert lanosterol to ergosterol. Inhibition of ergosterol results in increased cellular permeability causing leakage of cellular contents. Econazole may also inhibit endogenous respiration, interact with membrane phospholipids, inhibit the transformation of yeasts to mycelial forms, inhibit purine uptake, and impair triglyceride and phospholipid biosynthesis. |
产品性质
| Quality Level【质量水平】 | 200 |
| form【形式】 | powder or crystals |
| color【颜色】 | white to off-white |
| Mode of action【作用机制】 | cell membrane | interferes cell wall synthesis | interferes enzyme | inhibits |
| antibiotic activity spectrum【抗生素抗菌谱】 | Gram-positive bacteria fungi |
| SMILES string | O[N+]([O-])=O.Clc1ccc(COC(Cn2ccnc2)c3ccc(Cl)cc3Cl)cc1 |
| InChI | 1S/C18H15Cl3N2O.HNO3/c19-14-3-1-13(2-4-14)11-24-18(10-23-8-7-22-12-23)16-6-5-15(20)9-17(16)21;2-1(3)4/h1-9,12,18H,10-11H2;(H,2,3,4) |
| InChI key | DDXORDQKGIZAME-UHFFFAOYSA-N |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H302 - H315 - H319 |
| Precautionary Statements | P264 - P270 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338 |
| Hazard Classifications【危险分类】 | Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 |
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | dust mask type N95 (US), Eyeshields, Gloves |
