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依法克生 盐酸盐
Efaroxan hydrochloride
产品别名
89197-00-2
依法克生 盐酸盐
Efaroxan hydrochloride
RX 821037A
2-Ethyl-2-(imidazolin-2-yl)-2,3-dihydrobenzofuran hydrochloride
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C13H16N2O · HCl |
| Molecular weight | 252.74 |
| MDL number | MFCD00069270 |
| PubChem Substance ID【PubChem化学物质编号】 | 24278415 |
| Biochem/physiol Actions【生化/生理作用】 | (+)-Isomer is a selective α-adrenoceptor antagonist; (−)-isomer is an imidazoline ligand that induces insulin secretion, mediated by the blockade of ATP-sensitive potassium channels in pancreatic β cells; I1 imidazoline binding site antagonist. |
| Features and Benefits【特点和优势】 | This compound is featured on the Imidazoline Binding Sites and Potassium Channels pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| solubility【溶解性】 | H2O: >20 mg/mL |
| SMILES string | Cl.CCC1(Cc2ccccc2O1)C3=NCCN3 |
| InChI | 1S/C13H16N2O.ClH/c1-2-13(12-14-7-8-15-12)9-10-5-3-4-6-11(10)16-13;/h3-6H,2,7-9H2,1H3,(H,14,15);1H |
| InChI key | DWOIUCRHVWIHAH-UHFFFAOYSA-N |
| Gene Information | human ... ADRA1A(148), ADRA1B(147), ADRA1D(146), ADRA2A(150), ADRA2B(151), ADRA2C(152) |
| packaging【包装】 | 10, 50 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS06 |
| Signal word【警示用语：】 | Danger |
| Hazard Statements | H301 |
| Precautionary Statements | P301 + P310 |
| Hazard Classifications【危险分类】 | Acute Tox. 3 Oral |
| Storage Class Code【储存分类代码】 | 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
