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Eliprodil
产品别名
119431-25-3
Eliprodil
α-(4-Chlorophenyl)-4-[(4-fluorophenyl)methyl]-1-piperidineethanol
SL 820715
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C20H23ClFNO |
| Molecular weight | 347.85 |
| MDL number | MFCD00866651 |
| PubChem Substance ID【PubChem化学物质编号】 | 24277709 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | NR2B selective NMDA glutamate receptor antagonist which appears to target the "polyamine site" on the NMDA receptor, setting it apart from other NR2B receptor antagonists. Possesses neuroprotective effects in models of ischemia, but prolongs the QT interval in patients; currently under investigation for acute and chronic pain. |
| Features and Benefits【特点和优势】 | This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here. |
产品性质
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 5 mg/mL, clear H2O: insoluble |
| originator【创始人】 | Sanofi Aventis |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | OC(CN1CCC(CC1)Cc2ccc(F)cc2)c3ccc(Cl)cc3 |
| InChI | 1S/C20H23ClFNO/c21-18-5-3-17(4-6-18)20(24)14-23-11-9-16(10-12-23)13-15-1-7-19(22)8-2-15/h1-8,16,20,24H,9-14H2 |
| InChI key | GGUSQTSTQSHJAH-UHFFFAOYSA-N |
| Gene Information | human ... GRIN2B(2904) rat ... Adra1a(29412) |
| packaging【包装】 | 10, 50 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves |
