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依那普利 二水合物
Enalaprilat dihydrate
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3080934 | 5 MG | 1810 | |||
| 3080934 | 25 MG | 6220 |
产品别名
84680-54-6
依那普利 二水合物
Enalaprilat dihydrate
Vasotec
(2S)-1-[(2S)-2-[[(1S)-1-Carboxy-3-phenyl-propyl]amino]propanoyl]pyrrolidine-2-carboxylic acid
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C18H24N2O5 ·2H2O |
| Molecular weight | 384.42 |
| EC number【EC 号】 | 278-459-3 |
| MDL number | MFCD00941393 |
| PubChem Substance ID【PubChem化学物质编号】 | 329799089 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | Enalapril, the ethyl ester of enalaprilat exhibits slight pharmacological activity until it is hydrolyzed in the liver to enalaprilat. Enalaprilat, a IV form of an angiotensin-converting-enzyme inhibitor (ACE) prevents the transformation of angiotensin I to angiotensin II, a potent vasoconstrictor. Enalaprilat is an inhibitor of angiotensin converting enzyme (ACE), antihypertensive, and a Bradykinin B1 receptor activator. Enalaprilat has nM potency versus ACE and also activates B1 receptors to release NO. |
| Features and Benefits【特点和优势】 | This compound was developed by Merck & Co., Inc., Kenilworth, NJ, U.S.. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here. This compound is featured on the Angiotensin Receptors and Bradykinin Receptors pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| solubility【溶解性】 | H2O: 14 mg/mL at 60 ℃ (warming for 5 minutes) DMSO: 64 mg/mL |
| originator【创始人】 | Merck & Co., Inc., Kenilworth, NJ, U.S. |
| storage temp.【储存温度】 | room temp |
| SMILES string | O.O.C[C@H](N[C@@H](CCc1ccccc1)C(O)=O)C(=O)N2CCC[C@H]2C(O)=O |
| InChI | 1S/C18H24N2O5.2H2O/c1-12(16(21)20-11-5-8-15(20)18(24)25)19-14(17(22)23)10-9-13-6-3-2-4-7-13;;/h2-4,6-7,12,14-15,19H,5,8-11H2,1H3,(H,22,23)(H,24,25);2*1H2/t12-,14-,15-;;/m0../s1 |
| InChI key | MZYVOFLIPYDBGD-MLZQUWKJSA-N |
| Gene Information | human ... ACE(1636) |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |
