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ER-27319
产品别名
201010-95-9
ER-27319
10-(3-Aminopropyl)-3,4-dimethyl-9-acridone oxalate
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C20H22N2O5 |
| Molecular weight | 370.40 |
| MDL number | MFCD07784502 |
| PubChem Substance ID【PubChem化学物质编号】 | 24724472 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | ER-27319 inhibits Syk activation with an IC50 = 10 μM. ER-27319 inhibits Syk by preventing the phosphorylated ITAM domain of FcεRI γ from activating Syk. ER-27319 does NOT inhibit previously activated Syk. Selective Syk inhibitor. Induces tyrosine phosphorylation of Syk that has been demonstrated as critical for degranulation. |
| Features and Benefits【特点和优势】 | This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | solid |
| solubility【溶解性】 | DMSO: 28 mg/mL |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | OC(=O)C(O)=O.Cc1ccc2C(=O)c3ccccc3N(CCCN)c2c1C |
| InChI | 1S/C18H20N2O.C2H2O4/c1-12-8-9-15-17(13(12)2)20(11-5-10-19)16-7-4-3-6-14(16)18(15)21;3-1(4)2(5)6/h3-4,6-9H,5,10-11,19H2,1-2H3;(H,3,4)(H,5,6) |
| InChI key | IIELZHYJYZBSGG-UHFFFAOYSA-N |
| packaging【包装】 | 5 mg in glass bottle 25 mg in poly bottle |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H302 + H312 |
| Precautionary Statements | P264 - P270 - P280 - P301 + P312 - P302 + P352 + P312 - P362 + P364 |
| Hazard Classifications【危险分类】 | Acute Tox. 4 Dermal - Acute Tox. 4 Oral |
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 1 |
