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ErbB1/EGFR from mouse
产品编号: | 3081592 |
规格: | recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE) |
包装规格: | 10 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
ErbB1/EGFR from mouse
ERBB
mENA
PIG61
HER1
产品性质
biological source【生物来源】 | mouse |
recombinant【重组】 | expressed in HEK 293 cells |
tag【标签】 | 6-His tagged (C-terminus) |
Assay【测定】 | ≥95% (SDS-PAGE) |
form【形式】 | lyophilized |
mol wt【分子量】 | calculated mol wt 70 kDa observed mol wt 110-115 kDa by SDS-PAGE (DTT-reduced. Leu 25 is the predicted N-terminal .) |
packaging【包装】 | pkg of 10 μg |
impurities【杂质】 | <1 EU/μg endotoxin (LAL test) |
UniProt accession no.【UniProt登记号】 | Q01279 |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | mouse ... EGFR(13649) |
基本信息
General description【一般描述】 | The epidermal growth factor receptor (EGFR; ErbB-1; HER1) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/c-neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4). Mutations affecting EGFR expression or activity could result in cancer. |
Physical form【外形】 | Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Generally 5-8% Mannitol or trehalose is added as a protectant before lyophilization. |
Reconstitution【重悬】 | Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 μg/mL. Do not vortex. This solution can be stored at 2-8℃ for up to 1 month. For extended storage, it is recommended to store at -20℃. |
安全信息
Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
WGK | WGK 3 |