乙酰乙酸乙酯

CH₃COCH₂COOC₂H₅

130.14

385838

205-516-1

MFCD00009199

39022303

329747065

NA.22

Ethyl acetoacetate can be used as a reactant in the synthesis of:

• Knoevenagel condensation products by reacting with α-alkylideneacetoacetate and aliphatic, aromatic, heteroaromatic aldehydes.
• Michael adducts, via Michael addition reaction with chalcones and azachalcones in the presence of a base catalyst.
• Substituted nicotinic acid derivatives by treating with α, β-unsaturated oximes via Michael addition followed by ring closure reaction.

It can be also utilized as a reactant in the transesterification and asymmetric hydrogenation reactions to produce valuable products.

200

4.48 (vs air)

1 mmHg ( 28.5 ℃)

puriss. p.a.

≥99.0% (GC)

580 °F

9.5 %

≤0.5% water

n20/D 1.419

181 ℃ (lit.)

−43 ℃ (lit.)

water: soluble 130 g/L at 20 ℃

1.029 g/mL at 20 ℃ (lit.)

Al: ≤0.5 mg/kg
Ba: ≤0.1 mg/kg
Bi: ≤0.1 mg/kg
Ca: ≤0.5 mg/kg
Cd: ≤0.05 mg/kg
Co: ≤0.02 mg/kg
Cr: ≤0.02 mg/kg
Cu: ≤0.02 mg/kg
Fe: ≤0.1 mg/kg
K: ≤0.5 mg/kg
Li: ≤0.1 mg/kg
Mg: ≤0.1 mg/kg
Mn: ≤0.02 mg/kg
Mo: ≤0.1 mg/kg
Na: ≤0.5 mg/kg
Ni: ≤0.02 mg/kg
Pb: ≤0.1 mg/kg
Sr: ≤0.1 mg/kg
Zn: ≤0.5 mg/kg

CCOC(=O)CC(C)=O

1S/C6H10O3/c1-3-9-6(8)4-5(2)7/h3-4H2,1-2H3

XYIBRDXRRQCHLP-UHFFFAOYSA-N

10 - Combustible liquids

WGK 1

164.3 °F - closed cup

73.5 ℃ - closed cup

Eyeshields, Gloves, type ABEK (EN14387) respirator filter