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依替膦酸钠 二钠 水合物
Etidronate disodium hydrate
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3086328 | 10 MG | 1270 | |||
| 3086328 | 100 MG | 7270 |
产品别名
7414-83-7
依替膦酸钠 二钠 水合物
Etidronate disodium hydrate
Dihydrogen (1-hydroxyethylidene)bisphosphonate disodium hydrate
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C2H6Na2O7P2 · xH2O |
| Molecular weight | 249.99 (anhydrous basis) |
| EC number【EC 号】 | 231-025-7 |
| MDL number | MFCD00152567 |
| PubChem Substance ID【PubChem化学物质编号】 | 329820220 |
| NACRES | NA.77 |
| Application【应用】 | Etidronate disodium hydrate has been used in the synthesis of bisphosphonate derivatives of adenosine triphosphate (ATP)by T4 RNA ligase. It has also been sued to inhibit human farnesyl diphosphate synthase (FDPS). |
| Biochem/physiol Actions【生化/生理作用】 | Etidronate helps to guard chronic ocular hypertension prompted retinal oxidative stress. It stimulates the development of retinal ganglion cells through insulin-like growth factor 1 (IGF-1) signaling pathway. It may possess neuroprotective effects in in vivo and in vitro rat model of glaucoma. Etidronate belongs to bisphosphonates. Bisphosphonate antiresorptive agent. Less potent inhibitor of farnesyl diphosphate synthase (IC50 = 80 μM) as compared to the nitrogen containing bisphosphonates |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥97% (NMR) |
| form【形式】 | solid |
| color【颜色】 | white |
| mp | >300 ℃ |
| solubility【溶解性】 | H2O: ≥10 mg/mL |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | [Na+].[Na+].CC(O)(P(O)([O-])=O)P(O)([O-])=O |
| InChI | 1S/C2H8O7P2.2Na/c1-2(3,10(4,5)6)11(7,8)9;;/h3H,1H3,(H2,4,5,6)(H2,7,8,9);;/q;2*+1/p-2 |
| InChI key | GWBBVOVXJZATQQ-UHFFFAOYSA-L |
| packaging【包装】 | 10, 100 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H302 |
| Hazard Classifications【危险分类】 | Acute Tox. 4 Oral |
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 1 |
| Personal Protective Equipment【个人防护装备】 | dust mask type N95 (US), Eyeshields, Gloves |
