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依托泊苷

Etoposide for system suitability
产品编号:3086387
规格:European Pharmacopoeia (EP) Reference Standard
CAS NO:33419-42-0
包装规格:
产品类别:进口试剂
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
3086387 1380
产品别名

33419-42-0

依托泊苷

Etoposide for system suitability

VP-16-213

4′-Demethylepipodophyllotoxin 9-(4,6-O-ethylidene-β-D-glucopyranoside)

Etoposide

4′-去甲基表鬼臼毒素 -(4,6-O-亚乙基-β-D-吡喃葡萄糖苷)

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C29H32O13
Molecular weight
588.56
MDL number
MFCD00869325
PubChem Substance ID【PubChem化学物质编号】
329831385
NACRES
NA.24
General description【一般描述】
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Biochem/physiol Actions【生化/生理作用】
依托泊甙是一种抗肿瘤试剂,和拓扑异构酶II和DNA结合,增强DNA双链和单链剪切和可逆抑制解除。 在S期和G2期阻止细胞周期;诱导正常和肿瘤细胞系凋亡;抑制癌蛋白Mdm2的合成,引起Mdm2过量表达的肿瘤系细胞凋亡。
Caution【注意】
Please find SDS provided by EDQM here..
Other Notes【其他说明】
Sales restrictions may apply.
产品性质
grade【等级】
pharmaceutical primary standard
manufacturer/tradename
EDQM
application(s)
pharmaceutical (small molecule)
format【格式】
neat
storage temp.【储存温度】
2-8℃
SMILES string
COc1cc(cc(OC)c1O)[C@H]2[C@@H]3[C@H](COC3=O)[C@H](O[C@@H]4O[C@@H]5CO[C@@H](C)O[C@H]5[C@H](O)[C@H]4O)c6cc7OCOc7cc26
InChI
1S/C29H32O13/c1-11-36-9-20-27(40-11)24(31)25(32)29(41-20)42-26-14-7-17-16(38-10-39-17)6-13(14)21(22-15(26)8-37-28(22)33)12-4-18(34-2)23(30)19(5-12)35-3/h4-7,11,15,20-22,24-27,29-32H,8-10H2,1-3H3/t11-,15+,20-,21-,22+,24-,25-,26-,27-,29+/m1/s1
InChI key
VJJPUSNTGOMMGY-MRVIYFEKSA-N
Gene Information
human ... TOP2A(7153), TOP2B(7155)
packaging【包装】
Unit quantity: 10 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
安全信息
Pictograms【象形图】
GHS07,GHS08
Signal word【警示用语:】
Danger
Hazard Statements
H302 - H350 - H361d
Precautionary Statements
P201 - P202 - P264 - P270 - P301 + P312 - P308 + P313
Hazard Classifications【危险分类】
Acute Tox. 4 Oral - Carc. 1B - Repr. 2
Storage Class Code【储存分类代码】
6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
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