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泛昔洛韦
Famciclovir
| 产品编号： | 3086775 |
| 规格： | Pharmaceutical Secondary Standard; Certified Reference Material |
| CAS NO： | 104227-87-4 |
| 包装规格： | 1 G |
| 产品类别： | 进口试剂 |
| 品牌： | Supelco |
| 优惠价： | 立即咨询 |
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3086775 | 1 G | 2410 |
产品别名
104227-87-4
泛昔洛韦
Famciclovir
2-(2-(2-Amino-9H-purin-9-yl)ethyl)-1,3-propanediol diacetate ester
BRL 42810
2-[2-(2-氨基-9H-嘌呤-9-基)乙基]-1,3-丙二醇二乙酸酯
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C14H19N5O4 |
| Molecular weight | 321.33 |
| MDL number | MFCD00866964 |
| PubChem Substance ID【PubChem化学物质编号】 | 329823560 |
| NACRES | NA.24 |
| General description【一般描述】 | Famciclovir is an antiviral drug, which is predominantly used in the treatment of herpes virus infection. It is an inactive prodrug, which on administration, undergoes rapid biotransformation to penciclovir. Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. |
| Application【应用】 | These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. Famciclovir may be used as a reference standard for the determination of the analyte in bulk drug and pharmaceutical formulations by spectrophotometry and high performance liquid chromatography. |
| Biochem/physiol Actions【生化/生理作用】 | 泛昔洛韦是一种抗逆转录病毒鸟苷类似物，用于治疗疱疹病毒感染和乙肝。泛昔洛韦可迅速转化为喷昔洛韦。病毒胸苷激酶将喷昔洛韦磷酸化为单磷酸形式，然后细胞激酶又将其转换为三磷酸喷昔洛韦。喷昔洛韦三磷酸可竞争性抑制病毒 DNA 聚合酶，从而抑制病毒复制。长时间服用会形成耐药性；这通常表现为筛选出了一批 DNA 聚合酶基因逆转录酶结构域突变的预先存在的耐药性菌株。 |
| Analysis Note【分析说明】 | These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available. |
| Other Notes【其他说明】 | This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
| Footnote【附注】 | To see an example of a Certificate of Analysis for this material enter LRAC3254 in the Documents slot below. This is an example certificate only and may not be the lot that you receive. |
产品性质
| Quality Level【质量水平】 | 300 |
| grade【等级】 | certified reference material pharmaceutical secondary standard |
| CofA | current certificate can be downloaded |
| packaging【包装】 | pkg of 1 g |
| technique(s) | HPLC: suitable gas chromatography (GC): suitable |
| application(s) | pharmaceutical (small molecule) |
| format【格式】 | neat |
| pharmacopeia traceability【药典可追溯性】 | traceable to USP 1269152 |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | CC(=O)OCC(CCn1cnc2cnc(N)nc12)COC(C)=O |
| InChI | 1S/C14H19N5O4/c1-9(20)22-6-11(7-23-10(2)21)3-4-19-8-17-12-5-16-14(15)18-13(12)19/h5,8,11H,3-4,6-7H2,1-2H3,(H2,15,16,18) |
| InChI key | GGXKWVWZWMLJEH-UHFFFAOYSA-N |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
