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氟桂嗪 二盐酸盐
Flunarizine dihydrochloride
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3087839 | 1 G | 905 | |||
| 3087839 | 10 G | 4400 |
产品别名
30484-77-6
氟桂嗪 二盐酸盐
Flunarizine dihydrochloride
1-[Bis(4-fluorophenyl)methyl]-4-(3-phenyl-2-propenyl)piperazine dihydrochloride
1-[双(4-氟苯基)甲基]-4-(3-苯基-2-丙烯基)哌嗪 二盐酸盐
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C26H26F2N2 · 2HCl |
| Molecular weight | 477.42 |
| Beilstein | 4284243 |
| EC number【EC 号】 | 250-216-6 |
| MDL number | MFCD00058198 |
| PubChem Substance ID【PubChem化学物质编号】 | 24277835 |
| NACRES | NA.77 |
| General description【一般描述】 | Flunarizine has antihistamine, anticonvulsant and vestibular depressive properties. It protects endothelial cells from calcium overload-induced damage. Flunarizine is used to treat epilepsy, migraine prophylaxis, cerebral blood flow disturbances, peripheral vascular disease and vertigo. |
| Application【应用】 | Flunarizine dihydrochloride has been used to study the effect of flunarizine on epileptiform activity. It is also used to study its effect on high-potassium induced increase of intracellular free calcium. |
| Biochem/physiol Actions【生化/生理作用】 | 阻断 T 型 Ca2+/Na+ 通道；抑制嗜铬细胞中由 K+ 诱导的儿茶酚胺释放。 |
| Features and Benefits【特点和优势】 | This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here. |
产品性质
| Quality Level【质量水平】 | 200 |
| Assay【测定】 | ≥98% (TLC) |
| originator【创始人】 | Johnson & Johnson |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | Cl[H].Cl[H].Fc1ccc(cc1)C(N2CCN(CC2)C\C=C\c3ccccc3)c4ccc(F)cc4 |
| InChI | 1S/C26H26F2N2.2ClH/c27-24-12-8-22(9-13-24)26(23-10-14-25(28)15-11-23)30-19-17-29(18-20-30)16-4-7-21-5-2-1-3-6-21;;/h1-15,26H,16-20H2;2*1H/b7-4+;; |
| InChI key | RXKMOPXNWTYEHI-RDRKJGRWSA-N |
| packaging【包装】 | 1, 10 g in poly bottle |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H302 |
| Precautionary Statements | P264 - P270 - P301 + P312 - P501 |
| Hazard Classifications【危险分类】 | Acute Tox. 4 Oral |
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | dust mask type N95 (US), Eyeshields, Gloves |
