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Frovatriptan succinate monohydrate

产品编号:3089360
规格:≥97% (HPLC)
CAS NO:158930-17-7
包装规格:10 MG,50 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
308936010 MG1530
308936050 MG4490
产品别名

158930-17-7

Frovatriptan succinate monohydrate

R-(+) 3-Methylamino-6-carboxamido-1,2,3,4-tetrahydrocarbazole monosuccinate monohydrate

Frovatriptan succinate

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C14H17N3O · C4H6O4 · H2O
Molecular weight
379.41
MDL number
MFCD18251278
PubChem Substance ID【PubChem化学物质编号】
329825767
NACRES
NA.77
Biochem/physiol Actions【生化/生理作用】
During migraine condition, frovatriptan succinate monohydrate acts on extra cerebral, intracranial arteries and prevent excessive dilation of these vessels.
Frovatriptan is a serotonin 5HT-1B/1D-receptor agonist used to treat migraine. Frovatriptan has high affinity for the 5-HT(1B) and 5-HT(1D) receptors while affinity for 5-HT receptors other than 5-HT(1B/1D) is substantially lower with a pEC50 value of 8.2 for the 5-HT1B receptor, compared to a pEC50 value of 6.2 for the 5-HT7 receptor.
产品性质
Quality Level【质量水平】
100
Assay【测定】
≥97% (HPLC)
form【形式】
powder
storage condition【储存条件】
desiccated
color【颜色】
white to beige
solubility【溶解性】
H2O: 20 mg/mL, clear
storage temp.【储存温度】
2-8℃
SMILES string
OC(CCC(O)=O)=O.NC(C(C=C1)=CC2=C1NC3=C2C[C@H](NC)CC3)=O.O
InChI
1S/C14H17N3O.C4H6O4.H2O/c1-16-9-3-5-13-11(7-9)10-6-8(14(15)18)2-4-12(10)17-13;5-3(6)1-2-4(7)8;/h2,4,6,9,16-17H,3,5,7H2,1H3,(H2,15,18);1-2H2,(H,5,6)(H,7,8);1H2/t9-;;/m1../s1
InChI key
CUETXFMONOSVJA-KLQYNRQASA-N
Gene Information
human ... HTR1B(3351), HTR1D(3352)
packaging【包装】
10, 50 mg in glass bottle
安全信息
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 3
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