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γ-倒捻子素
gamma-Mangostin
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3090004 | 10 MG | 4850 | |||
| 3090004 | 50 MG | 13210 |
产品别名
31271-07-5
γ-倒捻子素
gamma-Mangostin
Normangostin
1,3,6,7-Tetrahydroxy-2,8-bis(3,3-dimethylallyl)xanthone
Demethylmangostin
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C23H24O6 |
| Molecular weight | 396.43 |
| MDL number | MFCD00951752 |
| NACRES | NA.25 |
| General description【一般描述】 | The fruit hulls of mangosteen contain three major bioactive compounds namely, α-, β-, and γ-mangostin. |
| Application【应用】 | γ-Mangostin has been used to study its inhibitory effect on Transthyretin (TTR) fibrillization, a homotetrameric protein involved in human hereditary amyloidosis. |
| Biochem/physiol Actions【生化/生理作用】 | The xanthone derivatives, namely α-, β-, and γ-mangostin have various biological activities including antiproliferative and anti-inflammatory activity, enhancement of natural killer (NK) cell activity, and antiviral effect against human immunodeficiency virus (HIV). γ-Mangostin is also reported to inhibit cyclooxygenase (COX-2) activity and NO production, which in turn reduces the level of prostaglandin E2. It is found to induce cell death in human colon cancer cells. Xanthone derivative isolated from the mangosteen hull (Garcinia mangostana). Exhibits antioxidant and anticancer properties. Mangosteen xanthones inhibit inflammation in human adipocytes which is important in understanding obesity-associated inflammation and the development of insulin resistance. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | off-white to yellow |
| solubility【溶解性】 | methanol: 1 mg/mL, colorless to yellow |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | OC1=CC(OC2=CC(O)=C(CC=C(C)C)C(O)=C2C3=O)=C3C(CC=C(C)C)=C1O |
| InChI | 1S/C23H24O6/c1-11(2)5-7-13-15(24)9-18-20(22(13)27)23(28)19-14(8-6-12(3)4)21(26)16(25)10-17(19)29-18/h5-6,9-10,24-27H,7-8H2,1-4H3 |
| InChI key | VEZXFTKZUMARDU-UHFFFAOYSA-N |
| packaging【包装】 | 10 mg in glass bottle 50 mg in poly bottle |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H302 |
| Precautionary Statements | P301 + P312 + P330 |
| Hazard Classifications【危险分类】 | Acute Tox. 4 Oral |
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
