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GKA50
产品别名
851884-87-2
GKA50
6-[[3-[(1S)-2-Methoxy-1-methylethoxy]-5-[(1S)-1-methyl-2-phenylethoxy]benzoyl]amino]-3-pyridinecarboxylic acid
基本信息
Empirical Formula【经验(实验)分子式】 | C26H28N2O6 |
Molecular weight | 464.51 |
NACRES | NA.77 |
Biochem/physiol Actions【生化/生理作用】 | GKA50 is a specific activator of glucokinase (EC50 = 0.03 μM). In mouse MIN6 insulin-secreting cells and rat pancreatic islet cells, GKA50 elicits a leftward shift in response to sub-maximal glucose concentrations as measured by insulin secretion and elevation of intracellular calcium levels. |
产品性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | ≥98% (HPLC) |
form【形式】 | powder |
color【颜色】 | white to beige |
solubility【溶解性】 | DMSO: 15 mg/mL, clear |
storage temp.【储存温度】 | −20℃ |
packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
Pictograms【象形图】 | GHS07 |
Signal word【警示用语:】 | Warning |
Hazard Statements | H302 - H413 |
Precautionary Statements | P273 - P301 + P312 + P330 |
Hazard Classifications【危险分类】 | Acute Tox. 4 Oral - Aquatic Chronic 4 |
Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
WGK | WGK 3 |