Goat anti-RENT1 Antibody, Affinity Purified

100

goat

affinity purified immunoglobulin

primary antibodies

Powered by Bethyl Laboratories, Inc.

mouse, human

1 mg/mL

immunoprecipitation (IP): 2-10 μg/mL
western blot: 1:2,000-1:10000

NP_002902.2

wet ice

2-8℃

goat ... UPF1(5976)

The epitope recognized by PLA0010 maps to a region between residue 1075 and the C-terminus (residue 1118) of human Regulator of Nonsense Transcripts 1 (up-frameshift mutation 1 homolog) using the numbering given in entry NP_002902.2 (GeneID 5976).

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% sodium azide

RENT1, also known as UPF1, is a key regulator of the nonsense-mediated mRNA decay (NMD) pathway. The NMD pathway eliminates mRNAs that prematurely terminate during translation and may serve to protect the cells from dominant-negative effects of truncated proteins, or as a means to regulate protein expression. RENT1 is an ATP-dependent 5′- 3′ RNA helicase and ATPase that localizes to the cytoplasm and is part of a post-splicing multiprotein complex as well as an mRNA decay complex.

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12 - Non Combustible Liquids

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