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GSK334429 hydrochloride
产品别名
799558-94-4
GSK334429 hydrochloride
1-(1-Methylethyl)-4-((1-(6-(trifluoromethyl)-3-pyridinyl)-4-piperidinyl)carbonyl)hexahydro-1H-1,4-diazepine hydrochloride
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C20H29F3N4O · xHCl |
| Molecular weight | 398.47 (free base basis) |
| MDL number | MFCD22666404 |
| PubChem Substance ID【PubChem化学物质编号】 | 329825449 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | GSK334429 is a selective histamine H3 receptor antagonist. H3 antagonists increase the release of brain histamine, ACh, NE and DA neurotransmitters that modulate cognitive processes. Studies look at their analgesic efffects including efficacy for neuropathic pain. |
| Features and Benefits【特点和优势】 | This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here. |
| Other Notes【其他说明】 | Store desiccated; dry room. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| storage condition【储存条件】 | desiccated |
| color【颜色】 | white to beige |
| solubility【溶解性】 | H2O: 5 mg/mL (clear solution) |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | Cl.CC(C)N1CCCN(CC1)C(=O)C2CCN(CC2)c3ccc(nc3)C(F)(F)F |
| InChI | 1S/C20H29F3N4O.ClH/c1-15(2)25-8-3-9-27(13-12-25)19(28)16-6-10-26(11-7-16)17-4-5-18(24-14-17)20(21,22)23;/h4-5,14-16H,3,6-13H2,1-2H3;1H |
| InChI key | RCZVWLOXPFGZDD-UHFFFAOYSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
