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GW-803430
产品别名
515141-51-2
GW-803430
6-(4-chloro-phenyl)-3-[3-methoxy-4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-3H-thieno[3,2-d]pyrimidin-4-one
GW-803430A
GW-3430
基本信息
| Empirical Formula【经验(实验)分子式】 | C25H24ClN3O3S |
| Molecular weight | 481.99 |
| NACRES | NA.77 |
| Application【应用】 | GW-803430 may be used in MCHR1-mediated cell signaling studies. |
| Biochem/physiol Actions【生化/生理作用】 | GW-803430 antagonizes central MCHR1 and produces anxiolytic, anti-depressant and anti-obesity effects in rats and mice. It also controls the alcohol-seeking behavior in rats and is a promising treatment for alcohol use-related disorders. GW-803430 is a centraly active and selective melanin-concentrating hormone receptor (MCHR) 1 antagonist |
| Features and Benefits【特点和优势】 | This compound is featured on the Melanin-Concentrating Hormone Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here. This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: ≥4 mg/mL at warmed to 60 ℃ |
| originator【创始人】 | GlaxoSmithKline |
| storage temp.【储存温度】 | 2-8℃ |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H302 - H319 |
| Precautionary Statements | P301 + P312 + P330 - P305 + P351 + P338 |
| Hazard Classifications【危险分类】 | Acute Tox. 4 Oral - Eye Irrit. 2 |
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
