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I-OMe-Tyrphostin AG 538
产品别名
I-OMe-Tyrphostin AG 538
α-Cyano-(3-methoxy-4-hydroxy-5-iodocinnamoyl)-(3′,4′-dihydroxyphenyl)ketone
I-OMe-AG 538
基本信息
| Empirical Formula【经验(实验)分子式】 | C17H12INO5 |
| Molecular weight | 437.19 |
| MDL number | MFCD03453582 |
| PubChem Substance ID【PubChem化学物质编号】 | 24278758 |
| NACRES | NA.77 |
| Application【应用】 | I-OMe-Tyrphostin AG 538 has been used as a cell signaling inhibitor in PC-1 cell lines. It has also been used in high throughput screening assays for IGF1R inhibitors. |
| Biochem/physiol Actions【生化/生理作用】 | Insulin growth factor 1 (IGF-1) receptor protein tyrosine kinase inhibitor. |
| Features and Benefits【特点和优势】 | This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm. |
| Preparation Note【制备说明】 | I-OMe-Tyrphostin AG 538 is soluble in DMSO at 50 mg/ml. |
产品性质
| Quality Level【质量水平】 | 100 |
| form【形式】 | solid |
| solubility【溶解性】 | DMSO: 50 mg/mL |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | COc1cc(cc(I)c1O)\C=C(/C#N)C(=O)c2ccc(O)c(O)c2 |
| InChI | 1S/C17H12INO5/c1-24-15-6-9(5-12(18)17(15)23)4-11(8-19)16(22)10-2-3-13(20)14(21)7-10/h2-7,20-21,23H,1H3/b11-4+ |
| InChI key | HSRMHXWCTRFVHK-NYYWCZLTSA-N |
| Gene Information | human ... IGF1(3479), IGF1R(3480) |
| packaging【包装】 | 5 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |
