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淫羊藿甙

Icariin
产品编号:3098012
规格:≥94% (HPLC)
CAS NO:489-32-7
包装规格:100 MG,1 G
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
3098012100 MG1950
30980121 G9600
产品别名

489-32-7

淫羊藿甙

Icariin

4′-O-methyl-8-γ,γ-dimethylallylkaempferol-3-rhamnoside-7-glucoside

4′-O-甲基-8-γ,γ-dimethylallylkaempferol-3-鼠李糖苷素-7-葡糖苷

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C33H40O15
Molecular weight
676.66
MDL number
MFCD00210516
PubChem Substance ID【PubChem化学物质编号】
329815347
NACRES
NA.25
General description【一般描述】
Icariin is a prenylated flavonol and the major bioactive compound found in Epimedium herb.
Application【应用】
Icariin has been used:
  • in the preparation of topical treatment to determine its effects on the improvement of cutaneous wound healing in rats
  • to test its analgesic effects on lower back pain (LBP) in rats
  • as a potential treatment in osteoporosis condition in rats
  • to study its effects on palmitate (PA)-induced insulin resistance in skeletal muscle C2C12 myotubes
  • as a neuroprotective agent to study its effects on amyloid-β (Aβ)-induced neuronal insulin resistance in human neuroblastoma SK-N-MC cells

Biochem/physiol Actions【生化/生理作用】
Icariin is a potent neuroprotective agent in neurodegenerative disorders and other disorders affecting the nervous system. It elicits anti-aging properties in unfertilized oocytes against age-related damage. Icariin exerts anti-inflammatory and antifibrotic properties aiding protection in chronic kidney disease (CKD)-associated renal fibrosis in mouse model. It also serves as an excellent antidiabetic and anti-atherosclerotic agent. Icariin is an excellent anti-cancer agent.
来源于淫羊藿属植物的黄酮类葡萄糖苷。该药理活性成分或其衍生物可促进骨形成、调节多药耐药性、增强神经元活力、刺激血管生成,并表现出抗氧化活性。
产品性质
Quality Level【质量水平】
100
Assay【测定】
≥94% (HPLC)
color【颜色】
light yellow to yellow
solubility【溶解性】
DMSO: 50 mg/mL, clear, colorless to dark yellow
storage temp.【储存温度】
room temp
SMILES string
COc1ccc(cc1)C2=C(O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](O)[C@H]3O)C(=O)c4c(O)cc(O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)c(C\C=C(\C)C)c4O2
InChI
1S/C33H40O15/c1-13(2)5-10-17-19(45-33-28(42)26(40)23(37)20(12-34)46-33)11-18(35)21-24(38)31(48-32-27(41)25(39)22(36)14(3)44-32)29(47-30(17)21)15-6-8-16(43-4)9-7-15/h5-9,11,14,20,22-23,25-28,32-37,39-42H,10,12H2,1-4H3/t14-,20+,22-,23+,25+,26-,27+,28+,32-,33+/m0/s1
InChI key
TZJALUIVHRYQQB-XLRXWWTNSA-N
packaging【包装】
100 mg in poly bottle
1 g in poly bottle
安全信息
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 3
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