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Idazoxan hydrochloride
产品别名
79944-56-2
Idazoxan hydrochloride
(±)-2-[1,4-Benzodioxan-2-yl]-2-imidazoline hydrochloride
RX 781094
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C11H12N2O2 · HCl |
| Molecular weight | 240.69 |
| MDL number | MFCD00069293 |
| PubChem Substance ID【PubChem化学物质编号】 | 24278493 |
| NACRES | NA.77 |
| Application【应用】 | Idazoxan hydrochloride has been used to study the efficacy of antidepressant treatments that interact with multiple neurotransmitter systems. |
| Biochem/physiol Actions【生化/生理作用】 | α2-adrenoceptor antagonist; I2 imidazoline receptor agonist; I1 imidazoline receptor antagonist. Idazoxan can antagonize various behaviors generated by ethanol in a preclinical setting. It possesses neuroprotective activity against spinal cord injury, resulted due to experimental autoimmune encephalomyelitis (EAE) in mouse, an animal modal of multiple sclerosis (MS). |
产品性质
| Quality Level【质量水平】 | 100 |
| solubility【溶解性】 | H2O: 50 mg/mL |
| SMILES string | Cl.C1CN=C(N1)C2COc3ccccc3O2 |
| InChI | 1S/C11H12N2O2.ClH/c1-2-4-9-8(3-1)14-7-10(15-9)11-12-5-6-13-11;/h1-4,10H,5-7H2,(H,12,13);1H |
| InChI key | MYUBYOVCLMEAOH-UHFFFAOYSA-N |
| Gene Information | human ... ADRA2A(150), ADRA2B(151), ADRA2C(152) |
安全信息
| Pictograms【象形图】 | GHS06 |
| Signal word【警示用语：】 | Danger |
| Hazard Statements | H301 |
| Precautionary Statements | P301 + P310 |
| Hazard Classifications【危险分类】 | Acute Tox. 3 Oral |
| Storage Class Code【储存分类代码】 | 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
