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产品别名
1141-41-9
IDT307
4-(4-Dimethylamino)phenyl-1-methylpyridinium iodide
4-[p-(Dimethylamino)phenyl]-1-methylpyridinium iodide
APP+
基本信息
| Empirical Formula【经验(实验)分子式】 | C14H17N2 · I |
| Molecular weight | 340.20 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | IDT307 (APP+) is a fluorescent analogue of the dopaminergic neurotoxin MPP+ monoamine transporter substrate that fluoresces after uptake into cells. IDT307 is a substrate for the dopamine transporter (DAT), norepinephrine transporter (NET), and serotonin transporter (SERT). IDT307 (APP+) was found to label catecholamine neuronal cell bodies with high selectivity in midbrain and was used to investigate SERT function in lymphocytes and platelets. |
| Features and Benefits【特点和优势】 | This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| storage condition【储存条件】 | desiccated |
| color【颜色】 | , orange to dark orange-red |
| solubility【溶解性】 | DMSO: 15 mg/mL, clear |
| storage temp.【储存温度】 | −20℃ |
| InChI | 1S/C14H17N2.HI/c1-15(2)14-6-4-12(5-7-14)13-8-10-16(3)11-9-13;/h4-11H,1-3H3;1H/q+1;/p-1 |
| InChI key | CAMWVBRDIKKGII-UHFFFAOYSA-M |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS06 |
| Signal word【警示用语：】 | Danger |
| Hazard Statements | H300 |
| Precautionary Statements | P264 - P301 + P310 |
| Hazard Classifications【危险分类】 | Acute Tox. 2 Oral |
| Storage Class Code【储存分类代码】 | 6.1B - Non-combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials |
| WGK | WGK 3 |
