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IL-19 from mouse
| 产品编号： | 3098299 |
| 规格： | recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC) |
| CAS NO： | 465617-97-4 |
| 包装规格： | 10 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
465617-97-4
IL-19 from mouse
MDA1
IL-10C
ZMDA1
Melanoma differentiation association like protein
NG.1
基本信息
| NACRES | NA.32 |
| General description【一般描述】 | IL19 (interleukin 19) belongs to the IL-10 family of cytokines, and shares high homology with IL-20 and IL-24 at the primary level. It is further subcategorized into a subfamily containing IL-19, IL-20, and IL-24. It was first discovered in 2001, and its expression is not only limited to leukocytes and is also expressed by angiogenic tissue. |
| Biochem/physiol Actions【生化/生理作用】 | IL19 (interleukin 19) promotes the production of pro-inflammatory cytokines, such as IL-6 and TNF-α, and therefore, participates in the pathogenesis of autoimmune diseases such as psoriasis, asthma, and rheumatoid arthritis. This protein functions as a strong pro-angiogenic influence on different human EC (endothelial cell) types, such as umbilical vein, coronary artery, and microvascular types. In Th2 (T helper)-mediated colitis rat model IL-19 functions as an anti-inflammatory agent, and might have potential as a therapeutic target for alleviating colonic inflammation. |
| Physical form【外形】 | Sterile filtered and lyophilized with no additives |
| Reconstitution【重悬】 | Centrifuge the vial prior to opening. Reconstitute in H?O to a concentration of 0.1-0.5 mg/ml. The solution can be diluted into other aqueous buffers |
产品性质
| biological source【生物来源】 | mouse |
| recombinant【重组】 | expressed in E. coli |
| Assay【测定】 | ≥95% (HPLC) ≥95% (SDS-PAGE) |
| form【形式】 | lyophilized |
| mol wt【分子量】 | 17.7 kDa |
| packaging【包装】 | pkg of 10 μg |
| impurities【杂质】 | Endotoxin, tested |
| NCBI accession no.【NCBI登记号】 | Q8CJ70 |
| UniProt accession no.【UniProt登记号】 | Q8CJ70 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | mouse ... IL19(329244) |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
