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kb-NB142-70
产品别名
1233533-04-4
kb-NB142-70
3,4-Dihydro-9-hydroxy-[1]benzothieno[2,3-f]-1,4-thiazepin-5(2H)-one
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C11H9NO2S2 |
| Molecular weight | 251.32 |
| MDL number | MFCD18086915 |
| PubChem Substance ID【PubChem化学物质编号】 | 329825531 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | kb-NB142-70 is a derivative of the PKD1 inhibitor CID755673, with approximately 6-fold greater potency (IC50 for inhibition of PKD1 = 28.3 nM vs. 182 nM for CID755673). kb-NB142-70 dose dependently inhibits proliferation of PC3 prostate cancer cell, and blocks migration of the prostate cancer lines PC3 and DU145. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥97% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 10 mg/mL, clear |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | Oc1ccc2sc3C(=O)NCCSc3c2c1 |
| InChI | 1S/C11H9NO2S2/c13-6-1-2-8-7(5-6)9-10(16-8)11(14)12-3-4-15-9/h1-2,5,13H,3-4H2,(H,12,14) |
| InChI key | DHUAGGSHTKPOHU-UHFFFAOYSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
