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KR-32568
| 产品编号： | 3102984 |
| 规格： | ≥98% (HPLC), solid |
| CAS NO： | 852146-73-7 |
| 包装规格： | 5 MG，25 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
852146-73-7
KR-32568
[5-(2-Methyl-5-fluorophenyl)furan-2-ylcarbonyl]guanidine
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C13H12FN3O2 |
| Molecular weight | 261.25 |
| MDL number | MFCD08705324 |
| PubChem Substance ID【PubChem化学物质编号】 | 24724522 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | Sodium/hydrogen exchanger-1 (NHE-1) inhibitor; IC50 = 0.23 μM; inhibited NHE-1-mediated rabbit platelet swelling; in anesthetized rats, reduced infarct size from 67% (control) to 43% (at 0.1 mg/kg) and 24% (at 1.0 mg/kg); reduced number of ventricular premature beats from 530 to 266 (at 0.1 mg/kg) and 115 (at 1.0 mg/kg); reduced ventricular fibrillation incidence from 17 to 8 (0.1 mg/kg) and 0 (1.0 mg/kg); implications for research and treatment of myocardial ischemic diseases. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | solid |
| color【颜色】 | white |
| solubility【溶解性】 | DMSO: ~10 mg/mL |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | Cc1ccc(F)cc1-c2ccc(o2)C(=O)NC(N)=N |
| InChI | 1S/C13H12FN3O2/c1-7-2-3-8(14)6-9(7)10-4-5-11(19-10)12(18)17-13(15)16/h2-6H,1H3,(H4,15,16,17,18) |
| InChI key | DTLDHYBZLVASJQ-UHFFFAOYSA-N |
| Gene Information | human ... SLC9A1(6548) |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H302 - H315 - H319 - H335 |
| Precautionary Statements | P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338 |
| Hazard Classifications【危险分类】 | Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
| Target Organs【靶器官】 | Respiratory system |
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter |
