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KY-05009
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3103033 | 5 MG | 1380 | |||
| 3103033 | 25 MG | 5070 |
产品别名
1228280-29-2
KY-05009
5-(4-Methylbenzamido)-2-(phenylamino)thiazole-4-carboxamide
5-[(4-Methylbenzoyl)amino]-2-(phenylamino)-4-thiazolecarboxamide
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C18H16N4O2S |
| Molecular weight | 352.41 |
| PubChem Substance ID【PubChem化学物质编号】 | 329825926 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | KY-05009 is a Traf2- and Nck-interacting kinase (TNIK) inhibitor that inhibits the epithelial-to-mesenchymal transition (EMT) in cancer cells. KY-05009 is also known as (5-(4-methylbenzamido)-2-(phenylamino) thiazole-4-carboxamide). It prevents the proliferation induced by interleukin-6 and promotes cell death by blocking Wnt signaling in multiple myeloma (MM) cells. KY-05009 is a novel aminothiazole, which possesses anti-cancer activity in human colorectal cancer cells. KY-05009 prevents migration and invasion stimulated by TGF-β1 (transforming growth factor beta 1). |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | light yellow to dark yellow |
| solubility【溶解性】 | DMSO: 10 mg/mL, clear |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | NC(C1=C(NC(C2=CC=C(C)C=C2)=O)SC(NC3=CC=CC=C3)=N1)=O |
| InChI | 1S/C18H16N4O2S/c1-11-7-9-12(10-8-11)16(24)22-17-14(15(19)23)21-18(25-17)20-13-5-3-2-4-6-13/h2-10H,1H3,(H2,19,23)(H,20,21)(H,22,24) |
| InChI key | WCEDGRTWDSHZHF-UHFFFAOYSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
