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L-trans-Pyrrolidine-2,4-dicarboxylic acid

产品编号:3103775
规格:≥98%
CAS NO:64769-66-0
包装规格:2 MG,10 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
31037752 MG1043
310377510 MG3070
产品别名

64769-66-0

L-trans-Pyrrolidine-2,4-dicarboxylic acid

L-trans-2,4-PDC

(2S,4R)-Pyrrolidine-2,4-Dicarboxylic Acid

trans-4-Carboxy-L-proline

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C6H9NO4
Molecular weight
159.14
MDL number
MFCD00153866
PubChem Substance ID【PubChem化学物质编号】
24898859
NACRES
NA.77
Application【应用】
L-trans-Pyrrolidine-2,4-dicarboxylic acid has been used:
  • as a glutamate transport inhibitor to test its impairing effect on glutamate-induced cell death in HT22 neuronal cells
  • as an analog of glutamate to test its effect on glutamate/glutamine-dependent acid resistance of E. coli and S. flexneri
  • as sodium glutamate (Na+/Glu) cotransporter inhibitor in myogenic cell line C2C12

Biochem/physiol Actions【生化/生理作用】
L-trans-Pyrrolidine-2,4-dicarboxylic acid is a selective glutamate transporter inhibitor.
产品性质
Quality Level【质量水平】
100
Assay【测定】
≥98%
SMILES string
OC(=O)[C@H]1CN[C@@H](C1)C(O)=O
InChI
1S/C6H9NO4/c8-5(9)3-1-4(6(10)11)7-2-3/h3-4,7H,1-2H2,(H,8,9)(H,10,11)/t3-,4+/m1/s1
InChI key
NRSBQSJHFYZIPH-DMTCNVIQSA-N
Gene Information
rat ... Gria1(50592), Grik1(29559), Grin2a(24409), Slc1a2(29482), Slc1a3(29483)
packaging【包装】
2, 10 mg in glass insert
安全信息
Pictograms【象形图】
GHS07
Signal word【警示用语:】
Warning
Hazard Statements
H315 - H319 - H335
Precautionary Statements
P302 + P352 - P305 + P351 + P338
Hazard Classifications【危险分类】
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs【靶器官】
Respiratory system
Storage Class Code【储存分类代码】
11 - Combustible Solids
WGK
WGK 3
Personal Protective Equipment【个人防护装备】
dust mask type N95 (US), Eyeshields, Gloves
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