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LAG-3 (mouse): FC (mouse)
| 产品编号： | 3104274 |
| 规格： | recombinant, expressed in CHO cells, >95% (SDS-PAGE) |
| 包装规格： | 50 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
LAG-3 (mouse): FC (mouse)
ACEH
Lymphocyte activation gene-3
FDC protein
基本信息
| NACRES | NA.32 |
| General description【一般描述】 | Lymphocyte activation gene 3 (LAG-3; CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4. |
| Physical form【外形】 | Solution in PBS. |
| Other Notes【其他说明】 | The sequence coding for the 4 extracellular Ig-like domains of mouse LAG-3 (D1-D4) is fused to the Fc portion of mouse IgG2a (hinge-CH2-CH3). |
产品性质
| biological source【生物来源】 | mouse |
| recombinant【重组】 | expressed in CHO cells |
| Assay【测定】 | >95% (SDS-PAGE) |
| form【形式】 | liquid |
| mol wt【分子量】 | monomer ~180 kDa by SDS-PAGE (non-reducing) monomer ~80 kDa by SDS-PAGE (reducing) |
| packaging【包装】 | pkg of 50 μg |
| storage condition【储存条件】 | avoid repeated freeze/thaw cycles |
| concentration【浓度】 | ≥0.2 mg/mL |
| impurities【杂质】 | <1 EU/μg endotoxin, tested |
| color【颜色】 | clear |
| UniProt accession no.【UniProt登记号】 | Q61790 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | mouse ... Lag3(16768) |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
