蜗牛凝集素

NA.32

Lectin from Helix pomatia is a hexameric glycoprotein with a molecular mass of 79 kDa. It issecreted by the albumen gland of the roman snail. Helix pomatia agglutinin (HPA) is specific for N-acetylgalactosamine (GalNAc).

Lectin from Helix pomatia has been used to conjugate with biotin and acridinium and used in lectin-agglutination tests.

Lectin from Helix pomatia protects fertilized eggs by coating them with perivitelline fluid. They exhibit antibacterial activities and immunity in snail. Helix pomatia agglutinin (HPA) possess the potential to agglutinate pathogens. HPA has also emerged as a marker of altered Oglycosylation in cancer.
HPA具有抗人A血型特异性，并且对末端N-乙酰基-α-D-半乳糖胺基残基具有亲和力。由亲和纯化的凝集素制备缀合物。

Affinity purified by a modification of the method of Hammarstrom and Kabat.

在报道中，凝集活性以μg/ml表示，用pH 6.8的磷酸盐缓冲液连续稀释1 mg/ml溶液进行测定。 该活性是指25℃孵育1小时后使2％人A型血红细胞混悬液凝集的最低浓度。

lyophilized powder

200

<4 μg per mL agglutination activity

salt, free

−20℃

1, 5 mg in glass bottle

13 - Non Combustible Solids

WGK 3

Eyeshields, Gloves, type N95 (US)