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LY-354740 水合物
LY-354740 hydrate
产品别名
LY-354740 水合物
LY-354740 hydrate
LY-354740
Eglumetad
(1S,2S,5R,6S)-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxy lic acid
Eglumegad
基本信息
| Empirical Formula【经验(实验)分子式】 | C8H11NO4 · xH2O |
| Molecular weight | 185.18 (anhydrous basis) |
| eCl@ss | 32160406 |
| NACRES | NA.77 |
| Application【应用】 | LY-354740 hydrate has been used as a metabotropic glutamate receptor group II/III agonist to study its behavioral effectsof electric shock on Gammarus fossarum. |
| Biochem/physiol Actions【生化/生理作用】 | LY-354740 is a highly selective and potent agonist of group II mGlu (metabotropic glutamate) receptors. It displays antianxiety and antiaddictive activity in vivo. It?s orally and systemically active. It is anxiolytic and inhibits symptoms of morphine withdrawal in morphine-dependent mice. |
| Features and Benefits【特点和优势】 | This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here. This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm. This compound was developed by Eli Lilly. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | solid |
| solubility【溶解性】 | deionized water: 8 mg/mL |
| originator【创始人】 | Eli Lilly |
| storage temp.【储存温度】 | room temp |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H302 |
| Hazard Classifications【危险分类】 | Acute Tox. 4 Oral |
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
