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Mephetyl tetrazole
产品别名
916923-10-9
Mephetyl tetrazole
1-[2-(4-Methoxyphenyl)ethyl]-5-(1-p-tolylcyclopropyl)-1H-tetrazole
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C20H22N4O |
| Molecular weight | 334.41 |
| MDL number | MFCD11045297 |
| PubChem Substance ID【PubChem化学物质编号】 | 329818044 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | Mephetyl tetrazole is a potent and selective Kv1.5 potassium channel blocker. IC50 = 330 nM; shows selective atrial prolongation (40%) of effective refractory period (ERP), but no effect on ventricular ERP Kv1.5 channel is a molecular target for the treatment of atrial fibrillation. |
| Features and Benefits【特点和优势】 | This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | oil |
| color【颜色】 | pale yellow |
| solubility【溶解性】 | DMSO: >5 mg/mL |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | COc1ccc(CCn2nnnc2C3(CC3)c4ccc(C)cc4)cc1 |
| InChI | 1S/C20H22N4O/c1-15-3-7-17(8-4-15)20(12-13-20)19-21-22-23-24(19)14-11-16-5-9-18(25-2)10-6-16/h3-10H,11-14H2,1-2H3 |
| InChI key | VREPWWBWXVLSEF-UHFFFAOYSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |
